Jamie R. Wallen

Wallen, Jamie


Department of Chemistry and Physics
Assistant Professor, Biochemistry

Phone: 828-227-2491
Email: jamiewallen@email.wcu.edu
Office Address: 316A Natural Sciences Building


Ph.D., Wake Forest University School of Medicine, 2008

B.S., Emory & Henry College, 2003

Areas of Interest:

DNA replication; protein-protein interactions that regulate fundamental biochemical processes; enzyme structure and function

Selected Publications:

Wallen, J.R., Majka, J. and Ellenberger, T. (2013) Discrete Interactions Between Bacteriophage T7 Primase-Helicase and DNA Polymerase Drive the Formation of a Priming Complex Containing Two Copies of DNA Polymerase. Biochemistry 52, 4026-4036.

Wallace, B.D., Edwards, J.S., Wallen, J.R., Moolman W.J., van der Westhuyzen, R., Strauss, E., Redinbo, M.R., and Claiborne, A. (2012) Turnover-Dependent Covalent Inactivation of Staphylococcus aureus Coenzyme A-Disulfide Reductase by Coenzyme A-Mimetics: Mechanistic and Structural Insights. Biochemistry 51, 7699-7711.

Wallen, J.R., Mallet, T.C., Boles, W., Parsonage, D., Furdui, C.M., Karplus, P.A., and Claiborne, A. (2009) Crystal Structure and Catalytic Properties of Bacillus anthracis CoADR-RHD: Implications for Flavin-Linked Sulfur Trafficking. Biochemistry 48, 9650-9667.

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