Michael W. Van Dyke
Department of Chemistry and Physics
Associate Professor, Biochemistry
Phone: 828-227-2286
Email: mvandyke@email.wcu.edu
Office Address: 332 Natural Sciences Building
Website:
Education:
- Ph.D., California Institute of Technology, 1984
- B.A., Monmouth College, 1979
Areas of Interest:
Ligand-nucleic acid interactions, combinatorial selection methods, technology development
Selected Publications:
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Van Dyke, M.W. REPSA: combinatorial approach for identifying preferred drug-DNA binding sequences. In “Drug-DNA Interaction: Second Edition” (Fox, K.R., ed.) Humana (Totowa, NJ) pp. 193–205, 2010.
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Van Dyke, N., Pickering, B.F., and Van Dyke, M.W. Stm1p affects translation by altering the ribosome association of eukaryotic elongation factor 3. Nucleic Acids Res. 37:6116-6125, 2009.
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Vashisht Gopal, Y.N., Chanchorn, E., and Van Dyke, M.W. Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions. Mol. Cancer Ther. 8:552-562, 2009.
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Van Dyke, M.W. Combinatorial Selection Methods. In: “Encyclopedia of Cancer” (Schwab, M., ed.) Springer (Berlin, Germany) pp. 731-735, 2009.
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Baby, J., Pickering, B.F., Vashisht Gopal, Y.N., and Van Dyke, M.W. Constitutive and inducible nuclear factor-kappaB in immortalized normal human bronchial epithelial and non-small cell lung cancer cell lines. Cancer Lett. 255:85-94, 2007.
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Vashisht Gopal, Y.N., Arora, T.A., and Van Dyke, M.W. Parthenolide specifically depletes histone deacetylase 1 protein and induces cell death through ataxia telangiectasia mutated. Chem. Biol. 14:813-823, 2007.
- Van Dyke, M.W., Van Dyke, N., and Sunavala-Dossabhoy, G. REPSA: general combinatorial
approach for identifying preferred ligand–DNA binding sequences. Methods 41:118-127, 2007.