Chris Coburn
Department of Biology
Assistant Professor
Phone: 828-227-2518
Fax: 828-227-7066
Email: ccoburn@wcu.edu
Office Address: Natural Science Building 132
Education:
- Ph.D., Physiology and Biophysics, SUNY Stony Brook, NY, 2000
- B.S., Physics, Tennessee Technological University, Cookeville, TN, 1991
Courses Taught:
- BIOL 291: “Human Anatomy and Physiology I”
- BIOL 292: “Human Anatomy and Physiology II”
- BIOL 311: “Animal Physiology”
Publications:
- Coburn, CT and Johnson, RA. (2004), Preparation and use of a [g-P32]-labeled nucleotide analog to identify and characterize protein kinase activities exhibiting unique substrate specificities. FASEB J 18(8), C37 Suppl. S.
- Coburn, CT and Abumrad, NA. (2003) Structure-function of CD36 and evidence for its role in facilitating membrane fatty acid transport. Chapter 1 in Cellular proteins and their ligand fatty acids in health and disease (Dutta-Roy, AK and Spener, F, eds.), pp. 1-25, VCH-Wiley.
- Febbraio M, Guy E, Coburn CT, Knapp FF, Beets AL, Abumrad NA, and Silverstein RL. (2002) The impact of overexpression and deficiency of fatty acid translocase (FAT)/CD36. Mol Cell Biochem 239(1-2), 193-7.
- Hajri, T, Ibrahimi, A, Coburn, CT, Knapp, FF, Kurtz, T, Pravenec, M and Abumrad, NA. (2001) Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy. J Biol Chem 276(26), 23661-6.
- Coburn, CT, Hajri, T, Ibrahimi, A and Abumrad, NA. (2001), Role of CD36 in membrane transport and utilization of long- chain fatty acids by different tissues. J Mol Neurosci 16(2-3), 117-121.
- Coburn, CT, Knapp, FF, Febbraio, M, Beets, AL, Silverstein, RL and Abumrad, NA. (2000), Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J Biol Chem 275(42), 32523-9.
- Abumrad, NA, Sfeir, Z, Connelly, MA and Coburn, C. (2000), Lipid transporters: membrane transport systems for cholesterol and fatty acids. Curr Opin Clin Nutr Metab Care 3(4), 255-262.
- Coburn, C, Beets, AL, Wang, F, Abumrad, N, Febbraio, M, Kropp, J and Knapp, FF. (1999), Use of BMIPP to probe CD36 glycoprotein activity in normal and CD36 knockout mice - Demonstration of significant differences in target organ uptake and lipid pool distribution. Eur J Nucl Med 26(9), PS121.
- Abumrad, N, Coburn, C and Ibrahimi, A. (1999), Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm. Biochim Biophys Acta 1441(1), 4-13.
- Baillie, AGS, Coburn, CT and Abumrad, NA. (1996), Reversible binding of long-chain fatty acids to purified FAT, the adipose CD36 homolog. J Membrane Biol 153(1), 75-81.